Journal of Clinical and Translational Hepatology

Journal of Clinical and Translational Hepatology

Thursday, 12 / 12 / 2019

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Procalcitonin and Liver Disease: A Literature Review

REVIEW ARTICLE

Procalcitonin and Liver Disease: A Literature Review

Ruolin Dong1, Bo Wan2, Su Lin2, Mingfang Wang2, Jiaofeng Huang2, Yinlian Wu2, Yilong Wu2, Nanwen Zhang3 and Yueyong Zhu*,1

1The First Affiliated Hospital of Fujian Medical University, Fuzhou, China
2Liver Research Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China
3Department of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, China
*Correspondence to: Yueyong Zhu, Liver Research Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China. Tel: +86-591-87981660, Fax: +86-591-83356180, E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Journal of Clinical and Translational Hepatology 2019;7(1):51-55 DOI: 10.14218/JCTH.2018.00012
Received: February 20, 2018 Accepted: October 23, 2018 Published online: November 23, 2018

Abstract

Procalcitonin (PCT) is a widely used biomarker for the diagnosis of bacterial infections. It is produced by various organs and the liver is considered to be the most important site of production. Severe liver dysfunction has been shown to influence PCT levels. Patients with no sources of infection who have liver disease are observed to have increased serum levels of PCT, thereby reducing the diagnostic utility and value within this particular patient subset. Here, we have summarized the relationship between PCT and liver disease, including liver cirrhosis, liver failure, and liver transplantation.

Keywords

Procalcitonin, Liver disease, Infection

 

 

 

Journal of Clinical and Translational Hepatology 2018 vol. 7, 51-55  [ Html ] [ PDF Full-text ]

 

© The Authors 2019. This article is published under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC 4.0), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license.

 

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